BiochemistrybioRxivPreprint
Discovery of an IKK2 Site that Allosterically Controls Its Activation
S. J. Hotchkiss, M. C. Mulero, G. J. Chan…·G. Ghosh
This paper identifies a novel allosteric site on IKK2 that can be targeted by small-molecule inhibitors to block its activity without ATP-competitive off-target effects.
DOI 10.1101/2021.01.27.428502