Author

H. Iwamoto

Florida Atlantic University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Physiology· 2 Biophysics· 1 Neuroscience· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Research Focus:cell type annotation· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:differential expression· 1 Assay:electronic health records· 1

Frequent Co-Authors

J. Ochala· 3 shared C. T. A. Lewis· 2 shared K. Campbell· 2 shared A. D'Amico· 1 shared A. E. Walsh· 1 shared A. Hau· 1 shared A. Hessel· 1 shared A. L. Hessel· 1 shared

Activity by Year

2021-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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3 shared papersPhysiology

J. Ochala

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Peripheral Inflammation Limits Serotonin Neuron Signaling Capacity via Serotonergic IL-1R1 to Reduce Neuronal Excitability and Enhance Serotonin Clearance

P. A. Gajewski, H. Iwamoto, Alaina N Tillman, Z. Filliben, A. E. Walsh, Nicole L. Baganz, Matthew James Robson, M. Zapata, Ning Quan, Randy Blakely

This study identifies how peripheral inflammation reduces serotonin neuron signaling through IL-1R1-mediated pathways, decreasing neuronal excitability and increasing serotonin clearance.

bioRxiv · Oct 13, 2025 · PreprintNeuroscience

Remodelling of Skeletal Muscle Myosin Metabolic States in Hibernating Mammals

C. T. A. Lewis, E. G. Melhedegaard, M. M. Ognjanovic, M. S. Olsen, J. Laitila, R. A. E. Seaborne, M. N. Gronset, C. Zhang, H. Iwamoto, A. L. Hessel, M. N. Kuehn, C. Merino, N. Amigo, O. Frobert, S. Giroud, , J. Ochala

This study examines changes in skeletal muscle myosin metabolic states during hibernation in different mammals, finding reduced ATP consumption and potential mechanisms for energy conservation.

bioRxiv · Nov 14, 2023 · PreprintPhysiology

Human light meromyosin mutations linked to skeletal myopathies disrupt the coiled coil structure and myosin head sequestration

G. Carrington, A. Hau, S. Kosta, H. Dugdale, F. Muntoni, A. D'Amico, P. Van den Bergh, N. Romero, E. Malfatti, J. J. Vilchez, A. Oldfors, S. Pajusalu, K. Ounap, M. Giralt-Pujol, E. Zanoteli, , J. Ochala

This study investigates how mutations in MYH7 and MYH2 genes affect myosin structure and function, finding that they disrupt coiled-coil structure and increase ATP consumption without affecting contractile function.

bioRxiv · May 15, 2023 · PreprintPhysiology

Predominant myosin super-relaxed state in canine myocardium with naturally occurring dilated cardiomyopathy

J. Ochala, C. T. A. Lewis, T. Beck, H. Iwamoto, A. Hessel, K. Campbell, G. Pyle

This study finds that myosin in DCM-affected dogs has increased super-relaxed state and is rescued by EMD-57033.

bioRxiv · Mar 10, 2023Pathology

The 3-D structure of fibrous material is fully restorable from its X-ray diffraction pattern

H. Iwamoto

This paper demonstrates that the 3-D structure of fibrous materials can be restored from their X-ray diffraction patterns without prior structural knowledge.

bioRxiv · Feb 9, 2021Biophysics