Structural insights of a highly potent pan-neutralizing SARS-CoV-2 human monoclonal antibody
J. L. Torres, G. Ozorowski, E. Andreano, H. Liu, J. Copps, G. Piccini, L. Donnici, M. Conti, C. Planchais, D. Planas, N. Manganaro, E. Pantano, I. Paciello, P. Pileri, T. Bruel, , A. B. Ward
The paper evaluates the potency of mAb J08 against SARS-CoV-2 variants using cell-based assays and cryo-EM, showing its resistance to escape mutations and broad binding capability.
Proceedings of the National Academy of Sciences · May 12, 2022Peer-reviewedImmunology