Author

M. D. Szczelkun

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:bacteria (other)· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

E. Kurilovich· 1 shared E. R. Westra· 1 shared F. M. Diffin· 1 shared G. Gasiunas· 1 shared G. Mullally· 1 shared K. Severinov· 1 shared K. van Aelst· 1 shared M. M. Naqvi· 1 shared

Activity by Year

2020-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 20 mutual co-author links

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1 shared paperMicrobiology

E. Kurilovich

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2 papers

Recent·Most cited

MicrobiologybioRxivPreprintMay 4, 2021

Bacteriostatic antibiotics promote the evolution of CRISPR-Cas immunity

T. Dimitriu, E. Kurilovich, U. Lapinska…·E. R. Westra

This study shows bacteriostatic antibiotics promote CRISPR-Cas immunity in Pseudomonas aeruginosa by slowing phage development and allowing more time for immune response.

DOI 10.1101/2021.05.04.442568

bacteria (other)experimental assay

𝕏 PostBluesky

BiochemistrybioRxivApr 9, 2020

5' modifications to CRISPR Cas9 gRNA can change the dynamics and size of R-loops and inhibit DNA cleavage

G. Mullally, K. van Aelst, M. M. Naqvi…·M. D. Szczelkun

The paper investigates how 5' modifications to CRISPR gRNA affect R-loop dynamics and DNA cleavage, finding that certain modifications inhibit cleavage while others do not.

DOI 10.1093/nar/gkaa477

experimental assay

𝕏 PostBluesky