U. Lapinska

Phage-induced efflux down-regulation boosts antibiotic efficacy

This study shows that phage presence reduces antibiotic efflux in bacteria, enhancing antibiotic efficacy and enabling lower concentrations for treatment.

Nutrient and salt depletion synergistically boosts glucose metabolism in individual bacteria

This study shows that nutrient and salt depletion in E. coli increases glucose accumulation rates at the translational and posttranslational levels, challenging the view that growth rate alone reflects metabolic status.

Membrane permeability differentiation at the lipid divide

This study compares membrane permeability between archaeal and bacterial lipids using vesicles and finds that archaeal diether lipids are more permeable than bacterial diester lipids.

CryoEM structure of the outer membrane secretin channel pIV from the f1 filamentous bacteriophage

The paper determines the cryo-EM structure of the phage secretin pIV from f1 bacteriophage, models its function, and compares it to bacterial secretins.

Bacteriostatic antibiotics promote the evolution of CRISPR-Cas immunity

This study shows bacteriostatic antibiotics promote CRISPR-Cas immunity in Pseudomonas aeruginosa by slowing phage development and allowing more time for immune response.