ImmunologybioRxiv
Fine-tuning spatial-temporal dynamics and surface receptor expression support plasma cell-intrinsic longevity
Z. Jing, P. Galbo, L. Ovando…·D. Fooksman
This study identifies unique features of long-lived plasma cells (LLPCs), including reduced motility, clustering, and specific surface markers, and shows that CXCR4 is critical for their survival and antibody production.
DOI 10.7554/elife.89712