IL-15 complex-induced IL-10 enhances Plasmodium-specific CD4+ Tfh differentiation and antibody production
M. Bravo, T. Dileepan, M. Dolan, J. Hildebrand, J. Wolford, S. E. Hamilton, A. E. Frosch, K. S. Burrack
This study shows that IL-15 complex treatment increases IL-10 in NK cells, which promotes Tfh differentiation and antibody production against Plasmodium, improving survival from reinfection.
bioRxiv · Oct 6, 2023 · PreprintImmunology