M. Long

Smartphone Placement Recognition during Walking: Performance Determinants and Real-World Generalizability

This paper develops and validates a classifier to recognize smartphone placement during walking, showing improved accuracy when aggregating pocket placements and highlighting performance variability across conditions.

Microsporidian Nosema bombycis secretes serine protease inhibitor to suppress host cell apoptosis via caspase BmICE

This paper identifies NbSPN14, a serine protease inhibitor secreted by Nosema bombycis, which inhibits host cell apoptosis by interacting with BmICE, providing insights into pathogen-host interactions.

Parallel Analyses by Mass Spectrometry (MS) and Reverse Phase Protein Array (RPPA) Reveal Complementary Proteomic Profiles in Triple-Negative Breast Cancer (TNBC) Patient Tissues and Cell Cultures

The paper compares Mass Spectrometry (MS) and Reverse Phase Protein Array (RPPA) in TNBC samples to assess their performance and identify complementary proteomic profiles.

Identification of potential inflammation markers for outgrowth of cow's milk allergy

The paper identifies potential inflammation markers in saliva samples of children with cow's milk allergy (CMA) that correlate with resolution or persistence of the allergy.

Cross-generational plasticity in Atlantic silversides (Menidia menidia) under the combined effects of hypoxia and acidification

This study shows that parental exposure to hypoxia and acidification alters offspring traits and gene expression, suggesting cross-generational plasticity in Atlantic silversides.

Repression of PRMT activities sensitize homologous recombination-proficient ovarian and breast cancer cells to PARP inhibitor treatment

This study identifies PRMT inhibitors as effective combinational therapies with PARP inhibitors to sensitize HR-proficient ovarian and breast cancer cells to treatment.

One million years of solitude: the rapid evolution of de novo protein structure and complex

This study examines the rapid structural evolution of de novo genes in rice over 1 million years, finding faster changes in disordered regions and structured elements compared to gene duplicates.

Evolutionarily new genes in humans with disease phenotypes reveal functional enrichment patterns shaped by adaptive innovation and sexual selection.

This study identifies evolutionarily new genes in humans with disease phenotypes, showing their enrichment in male reproductive diseases and adaptive traits like brain size and color vision.

Enterocytozoon hepatopenaei Proliferate in Procambarus clarkii: A Warning for Crayfish and Shrimp Aquaculture

This study shows that crayfish (Procambarus clarkii) can harbor and transmit the microsporidian parasite Enterocytozoon hepatopenaei, posing a risk to shrimp farming.

Microsporidia dressing up: the spore polaroplast transport through the polar tube and transformation into the sporoplasm membrane

This study investigates the formation of the sporoplasm membrane during microsporidia spore germination, revealing that the polaroplast transforms into the sporoplasm membrane via the polar tube.

Integrated single-cell analysis defines the epigenetic basis of castration-resistant prostate luminal cells

The paper uses multi-omics single-cell data to define the epigenetic basis of castration-resistant prostate luminal cells in mice and identifies key molecular pathways involved.

New gene evolution with subcellular expression patterns detected in PacBio-sequenced genomes of Drosophila genus

The paper analyzes gene age and subcellular expression patterns in Drosophila species using PacBio sequencing, finding new genes enriched in extracellular compartments and old genes in mitochondria and plasma membrane.

The 3-Dimensional Genome Drives the Evolution of Asymmetric Gene Duplicates via Enhancer Capture-Divergence

This paper shows that enhancer capture-divergence (ECD) is a significant evolutionary mechanism for asymmetric, distally duplicated genes, using Drosophila HP6/Umbrea as an example.

Analysis of D- and L- Isomers of (Meth)amphetamine in Human K2EDTA Plasma

The paper develops and validates a method to determine D- and L-isomer concentrations of methamphetamine in human K2EDTA plasma using LC-MS/MS.

Quantifying 64 drugs, illicit substances, and D- and L- isomers in human oral fluid with liquid-liquid extraction

This paper develops a low-cost, sensitive method for detecting 64 drugs and substances in human oral fluid using liquid-liquid extraction and LC-MS/MS.

Immunoglobulin-producing AT2-like cells secrete IgA into the extracellular matrix in pulmonary fibrosis

The paper identifies IgA-secreting AT2-like cells in fibrotic lungs and shows their role in ECM IgA deposition through spatial transcriptomics and scRNA-seq.

Rapid gene evolution in an ancient post-transcriptional and translationalregulatory system compensates for meiotic X chromosomal inactivation

This study shows that recently evolved genes in Drosophila compensate for meiotic X chromosomal inactivation by rapidly adapting in post-transcriptional and translational regulation.

Acquired resistance to PD-L1 inhibition is associated with an enhanced type I IFN-stimulated secretory program in tumor cells

This study identifies an IFN-stimulated secretory program in PD-L1-resistant tumors that promotes immune evasion and shows that targeting this program can inhibit tumor growth.

Species-specific gene duplication in Arabidopsis thaliana evolved novel phenotypic effects on morphological traits under strong positive selection

This study identifies a young gene in Arabidopsis thaliana that shows strong positive selection and contributes to morphological trait divergence through neofunctionalization.

Dinophyceae use exudates as weapons against the parasite Amoebophrya sp. (Syndiniales)

The paper shows that exudates from resistant Dinophyceae species inhibit the parasite Amoebophrya sp., reducing its survival and progeny without physical contact.

Evolutionary patterns of the chimerical retrogenes in Oryza

This study examines the evolutionary patterns of chimerical retrogenes in rice, finding that parental genes undergo positive selection after retrogene origination and that chimerical retrogenes are more positively selected than regular genes.

Neutrophil microvesicles drive atherosclerosis by delivering miR-155 to atheroprone endothelium.

The paper shows neutrophil microvesicles deliver miR-155 to atheroprone endothelium, promoting vascular inflammation and atherosclerosis in mice.

Baculovirus utilizes cholesterol transporter Niemann-Pick C1 for host cell entry

This study identifies BmNPC1 as a critical host receptor for baculovirus infection, showing its interaction with the viral glycoprotein gp64 and role in endosomal fusion.

Rapid evolution of gained essential developmental functions of a young gene via interactions with other essential genes

This study identifies a young gene in Drosophila that rapidly became essential through interactions with other essential genes.