Ribonucleotide reductase, a novel target for gonorrhea
J. Narasimhan, S. Letinski, S. Jung, A. Gerasyuto, J. Wang, M. Arnold, G. Chen, J. Hedrick, M. Dumble, K. Ravichandran, T. Levitz, C. Cui, C. L. Drennan, J. Stubbe, G. Karp, A. Branstrom
This study identifies two novel inhibitors of Neisseria gonorrhoeae that target ribonucleotide reductase, showing efficacy against multidrug-resistant strains in a mouse model.
bioRxiv · Nov 19, 2020Microbiology