ImmunologybioRxivPreprint
Type I IFN signaling in the absence of IRGM1 promotes M. tuberculosis replication in immune cells by suppressing T cell responses
S. K. Naik, M. E. McNehlan, Y. Mreyoud…·C. L. Stallings
This study shows that IRGM1 deletion increases type I IFN signaling, which suppresses T cell responses and promotes M. tuberculosis replication in immune cells.
DOI 10.1101/2023.10.03.560720