M. F. Hagan

This study introduces a synthetic cell model with an active cytoskeleton that exhibits shape fluctuations and morphing abilities, revealing how active forces influence membrane deformation dynamics.

This study investigates how liquid-liquid phase separation affects reversible self-assembly, finding it can enhance assembly rates and robustness against kinetic traps.

The paper investigates how ionic strength affects SV40-like VLP assembly using SAXS, cryo-TEM, and Brownian dynamics simulations, revealing structural changes with ionic strength variations.

This study uses computational models to simulate HBV capsid assembly and identifies factors controlling its dimorphism.

This paper uses simulations to study how protein shells assemble around multicomponent fluid cargoes, showing that interaction strengths affect encapsulation and organization.

This study uses simulations to show that steric interactions and surface roughness in active filament arrays can generate synchronized oscillations, metachronal waves, and jammed clusters.

The paper develops a computational model to study how scaffold proteins influence the assembly and size control of protein shells around cargo molecules, with implications for synthetic biology and cellular organization.

The paper explains that the stalling of enveloped virus budding is due to a geometrical energy barrier caused by curvature conflicts between the viral capsid and the neck region, which can be overcome by the ESCRT machinery.