Author

A. Zlotnick

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Microbiology· 2 Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:protein folding & dynamics· 2 Research Focus:cell signaling & trafficking· 1 Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Approach:simulation· 1

Frequent Co-Authors

C. J. Schlicksup· 2 shared A. J. Patterson· 1 shared B. Bothner· 1 shared B. Tyukodi· 1 shared C. Kim· 1 shared C. Schlicksup· 1 shared C.-Y. J. Wang· 1 shared F. Mohajerani· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersBiophysics

C. J. Schlicksup

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

BiophysicsbioRxivFeb 23, 2022

Multiscale Modeling of Hepatitis B Virus Capsid Assembly and its Dimorphism

F. Mohajerani, B. Tyukodi, C. J. Schlicksup…·M. F. Hagan

This study uses computational models to simulate HBV capsid assembly and identifies factors controlling its dimorphism.

DOI 10.1021/acsnano.2c02119

deep learningstatistical model

𝕏 PostBluesky

MicrobiologybioRxivPreprintAug 16, 2021

Core Protein-Directed Antivirals and Importinβ Can Synergistically Disrupt HBV Capsids

C. Kim, L. F. Barnes, C. J. Schlicksup…·A. Zlotnick

This study shows that HAP12, a CpAM antiviral, synergizes with importinβ to disrupt HBV capsids, revealing an unexpected mechanism of action involving host protein-induced catalysis.

DOI 10.1101/2021.08.16.456586

humanexperimental assay

𝕏 PostBluesky

BiochemistrybioRxivJan 24, 2020

Local stabilization of subunit-subunit contacts causes global destabilization of Hepatitis B virus capsids

C. Schlicksup, P. Laughlin, S. Dunkelbarger…·A. Zlotnick

This study investigates how DBT1, a dibenzothiazapine, affects HBV capsid stability by stabilizing subunit contacts and inducing structural asymmetry, leading to capsid disassembly.

DOI 10.1021/acschembio.0c00320

virusstructural biology

𝕏 PostBluesky

MicrobiologybioRxivPreprintSep 19, 2019

Identification of Chikungunya virus nucleocapsid core assembly modulators

S. E. Jones-Burrage, Z. Tan, L. Li…·S. Mukhopadhyay

The paper identifies small molecules that modulate Chikungunya virus nucleocapsid core assembly and inhibit virus production in cell culture.

DOI 10.1101/774943

experimental assaydrug response / drug discovery

𝕏 PostBluesky