L. Mahadevan

PEX1 is essential for the glycosome biogenesis and trypanosomatid parasite survival.

This study identifies TbPEX1 as essential for glycosome biogenesis and trypanosome survival, showing its role in matrix protein import and quality control mechanisms.

Beak morphometry and morphogenesis across avian radiations

The paper quantifies beak and skull shapes in birds to show how geometric parameters correlate with diet and how a growth law explains beak morphogenesis in adaptive radiations.

Active hydraulics and odd elasticity of muscle fibers

This study develops a multiscale model of muscle as an active sponge to explain contraction dynamics, highlighting hydraulic oscillations and nonreciprocal viscoelasticity.

Matrix viscoelasticity controls spatio-temporal tissue organization

This study shows how matrix viscoelasticity influences tissue organization by causing symmetry breaking and branching in epithelial cell aggregates.

Effective elasticity and persistence of strain in active filament-motor assemblies

This study investigates the persistence length of strain in active filament-motor assemblies, finding it depends on passive elasticity and motor kinetics under different deformation conditions.

Viscous effects and complex local flow behaviors dominate hemolymph circulation in the living wings of locusts

This study quantitatively maps hemolymph flow in locust wings, revealing complex local flow behaviors dominated by viscous effects.

Thermoregulatory morphodynamics of honeybee clusters

This study quantifies how honeybee swarm clusters change shape and size in response to temperature variations, revealing hysteretic and anisotropic morphological responses.

Image classification and cognition using contour curvature statistics

This study proposes that normalized contour curvature (NCC) distributions can represent and classify object categories, showing robustness to illumination and viewpoint changes.

Cooperative escape in ants and robots

This study examines cooperative escape behavior in ants and robots, showing how simple rules lead to collective problem-solving in dynamic environments.

Genetic architecture of floral traits in bee- and hummingbird-pollinated sister species of Aquilegia (columbine)

The paper identifies the genetic basis of a pollination syndrome shift in Aquilegia, finding complex genetic architectures for floral color and nectar traits, and a single locus for nectar spur curvature.

Synchronized oscillations, metachronal waves, and jammed clusters in sterically interacting active filament arrays

This study uses simulations to show that steric interactions and surface roughness in active filament arrays can generate synchronized oscillations, metachronal waves, and jammed clusters.

Liquid condensates increase potency of amyloid fibril inhibitors

The paper investigates how liquid condensates enhance the potency of amyloid fibril inhibitors by colocalizing inhibitors and aggregates within condensates.

Biophysical principles of choanoflagellate self-organization

The paper quantifies biophysical processes in choanoflagellate rosette morphogenesis, showing ECM constraints drive 3D growth and shape colony morphospace.

Filament extensibility and shear stiffening control persistence of strain and loss of coherence in cross-linked motor-filament assemblies

The paper investigates how filament extensibility and shear stiffening affect strain persistence and coherence loss in cross-linked motor-filament assemblies using theoretical and simulation approaches.

Spatiotemporal Integration in Plant Tropisms

This study develops a mathematical model to explain how plant shoots integrate temporal history of light and gravity stimuli to guide growth.

Size, shape and structure of insect wings

The paper analyzes insect wing morphology across multiple dimensions to define morphospaces and explore diversity across insect orders.

Optimal strategies for inhibition of protein aggregation

The paper uses aggregation kinetics and control theory to determine optimal drug protocols for inhibiting protein aggregation, finding different strategies are needed for primary and fibril-dependent secondary nucleation.

Dynamics of spreading microbial swarms and films

This study develops a two-phase thin-film model to explain bacterial swarm and biofilm dynamics by integrating hydrodynamics, osmotic flux, and nutrient transport.

Collective mechanical adaptation of honeybee swarms

This study investigates how honeybee swarms adapt mechanically to dynamic stimuli by changing their shape to improve stability.

The statistical nature of geometric reasoning

This paper investigates geometric reasoning by analyzing errors in triangle completion tasks, finding scale-dependent statistical patterns that contradict innate Euclidean rule theories.

The dynamics of sperm cooperation in a competitive environment

The paper studies sperm cooperation in Peromyscus rodents, showing optimal aggregate size for velocity and linking it to mating system differences.