Heterogeneity in the transcriptional response of the human pathogen Aspergillus fumigatus to the antifungal agent caspofungin
A. C. Colabardini, F. Wang, Z. Dong, L. Pardeshi, M. C. Rocha, J. H. Costa, T. F. dos Reis, A. Brown, Q. Z. Jaber, M. Fridman, T. Fill, A. Rokas, I. Malavazi, K. H. Wong, G. H. Goldman
This study investigates transcriptional heterogeneity in Aspergillus fumigatus strains responding to caspofungin, identifying a core response and variable response linked to secondary metabolite biosynthesis and iron homeostasis.
bioRxiv · Jul 15, 2021Microbiology