Dual G9A and EZH2 inhibition stimulates an anti-tumour immune response in ovarian high-grade serous carcinoma
P. Spiliopoulou, S. Spear, H. Mirza, I. Garner, L. Mcgarry, F. Grundland-Freile, Z. Cheng, D. Ennis, S. McNamara, M. Natoli, S. Mason, K. Blyth, P. Adams, P. Roxburgh, M. Fuchter, , I. McNeish
This study shows that dual inhibition of G9A and EZH2 in ovarian cancer enhances anti-tumour immune responses by altering the immune microenvironment and reducing tumour growth.
bioRxiv · May 9, 2021Cancer Biology