Author

P. Adams

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2 Bioengineering· 1 Cell Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 5 Assay:proteomics· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:cancer & tumor microenvironment· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2

Frequent Co-Authors

A. Bagchi· 1 shared A. Deshpande· 1 shared A. Eudes· 1 shared A. Mukhopadhyay· 1 shared A. Rosa Campos· 1 shared A. S. Bais· 1 shared B. A. Simmons· 1 shared B. Chen· 1 shared

Activity by Year

2018-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. Bagchi

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The anti-caspase 1 inhibitor VX-765 reduces immune activation, CD4+ T cell depletion, viral load and total HIV-1 DNA in HIV-1 infected humanized mice

M. Amand, P. Adams, R. Schober, G. Iserentant, J.-Y. Servais, M. Moutschen, C. Seguin-Devaux

bioRxiv · Sep 1, 2022Immunology

iPSC modeling shows uncompensated mitochondrial mediated oxidative stress underlies early heart failure in hypoplastic left heart syndrome

X. Xu, K. Jin, A. S. Bais, W. Zhu, H. Yagi, T. N. Feinstein, P. Nguyen, J. Criscione, X. Liu, G. Beutner, K. B. Karunakaran, P. Adams, C. K. Kuo, D. Kostka, G. S. Pryhuber, , C. W. Lo

This study uses iPSC-derived cardiomyocytes to show that mitochondrial oxidative stress and ER stress underlie early heart failure in HLHS patients.

bioRxiv · May 9, 2021 · PreprintCell Biology

Dual G9A and EZH2 inhibition stimulates an anti-tumour immune response in ovarian high-grade serous carcinoma

P. Spiliopoulou, S. Spear, H. Mirza, I. Garner, L. Mcgarry, F. Grundland-Freile, Z. Cheng, D. Ennis, S. McNamara, M. Natoli, S. Mason, K. Blyth, P. Adams, P. Roxburgh, M. Fuchter, , I. McNeish

This study shows that dual inhibition of G9A and EZH2 in ovarian cancer enhances anti-tumour immune responses by altering the immune microenvironment and reducing tumour growth.

bioRxiv · May 9, 2021Cancer Biology

A JAK/STAT-Mediated Inflammatory Signaling Cascade Drives Oncogenesis In AF10-Rearranged AML

B. Chen, A. Deshpande, K. O. Barbosa, M. Kleppe, X. Lei, N. Yeddula, A. Rosa Campos, R. Wechsler-Reya, A. Bagchi, S. Meshinchi, C. J. Eaves, I. Jeremias, T. Haferlach, D. Frank, Z. Ronai, , A. Deshpande

This study identifies JAK1 as a therapeutic target in AF10-rearranged AML by showing its role in JAK/STAT-mediated inflammatory signaling and oncogenesis.

bioRxiv · Aug 31, 2020Cancer Biology

Methyl ketone production by Pseudomonas putida is enhanced by plant-derived amino acids

J. Dong, Y. Chen, V. T. Benites, E. Baidoo, C. Petzold, H. Beller, A. Eudes, H. Scheller, P. Adams, A. Mukhopadhyay, B. A. Simmons, S. W. Singer

This study enhances methyl ketone production in Pseudomonas putida using plant-derived amino acids from hydrolysates, achieving a 9-fold increase in titer.

bioRxiv · Dec 13, 2018Bioengineering