MicrobiologybioRxiv
A virion-based assay for glycoprotein thermostability reveals key determinants of filovirus entry and its inhibition
R. H. Bortz, A. C. Wong, M. G. Grodus…·K. Chandran
This paper introduces an ELISA-based assay to measure the thermostability of filovirus glycoproteins, revealing how proteolytic cleavage, acid pH, and small-molecule inhibitors affect GP stability and viral entry.
DOI 10.1128/jvi.00336-20