Tumor necrosis factor is a necroptosis-associated alarmin
F. Pinci, M. Gaidt, C. Jung, D. Nagl, G. Kuut, V. Hornung
This study identifies TNF as a necroptosis-associated alarmin by showing that necroptosis promotes TNF translation and release through ADAM protease activation.
bioRxiv · Aug 1, 2022 · PreprintImmunology