ImmunologybioRxivPreprint
IRF5 promotes intestinal inflammation by guiding monocyte differentiation towards a pathogenic CD11c+ macrophage phenotype
A. L. Corbin, M. Gomez-Vazquez, T. E. Khoyratty…·I. A. Udalova
This study shows IRF5 promotes pathogenic CD11c+ macrophage differentiation from monocytes in the gut, worsening inflammation during colitis.
DOI 10.1101/601963