M. Groll

Identification, structure and function of the methyltransferase involved in the biosynthesis of the dithiolopyrrolone antibiotic xenorhabdin

This study identifies and characterizes XrdM, an amide methyltransferase involved in dithiolopyrrolone antibiotic biosynthesis, and shows it is distinct from DtpM in structure and function.

Global analysis of biosynthetic gene clusters reveals conserved and unique natural products in entomopathogenic nematode-symbiotic bacteria

The paper analyzes biosynthetic gene clusters in entomopathogenic nematode-symbiotic bacteria to identify conserved and unique natural products and their functional roles.

Cooperative DNA base and shape recognition by the CCAAT-binding complex and its bZIP transcription factor HapX

This study reports two crystal structures of the CBC-HapX complex bound to DNA, revealing how HapX interacts with DNA and the CBC to regulate gene expression in fungi.

PINK1-dependent phosphorylation of Serine111 within the SF3 motif of Rab GTPases impairs effector interactions and LRRK2 mediated phosphorylation at Threonine72

This study shows that PINK1 phosphorylates Rab GTPases at Ser111, which inhibits LRRK2-mediated phosphorylation at Thr72, suggesting PINK1 activators could treat LRRK2-related Parkinson's.