ImmunologybioRxiv
Direct tissue sensing reprograms TLR4+ Tfh-like cells inflammatory profile in the joints of rheumatoid arthritis patients
D. Amaral-Silva, R. C. Torrao, R. Torres…·H. Soares
The paper identifies TLR4+ Tfh-like cells in RA patients that switch from producing IL-21 to IL-17 upon joint exposure, contributing to tissue damage.
DOI 10.1038/s42003-021-02659-0