CAR Tregs mediate linked suppression and infectious tolerance in islet transplantation
C. Wardell, V. Fung, E. Chen, M. Haque, J. Gillies, J. Spanier, M. Mojibian, B. T. Fife, M. K. Levings
A2-CAR Tregs reduce BDC2.5 T cell engraftment, proliferation, and cytokine production, protecting mice from diabetes and inducing systemic tolerance.
bioRxiv · Apr 6, 2024 · PreprintImmunology