Author

J. Spanier

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:proteomics· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Research Focus:development & morphogenesis· 1 Assay:flow cytometry· 1

Frequent Co-Authors

A. Charpenay· 1 shared B. Horvat· 1 shared B. T. Fife· 1 shared C. Dumont· 1 shared C. Mathieu· 1 shared C. Wardell· 1 shared D. Gerlier· 1 shared E. Chen· 1 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. Charpenay

Mutual co-authors in cluster

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2 papers

Recent·Most cited

CAR Tregs mediate linked suppression and infectious tolerance in islet transplantation

C. Wardell, V. Fung, E. Chen, M. Haque, J. Gillies, J. Spanier, M. Mojibian, B. T. Fife, M. K. Levings

A2-CAR Tregs reduce BDC2.5 T cell engraftment, proliferation, and cytokine production, protecting mice from diabetes and inducing systemic tolerance.

bioRxiv · Apr 6, 2024 · PreprintImmunology

Activation of cGAS/STING pathway upon paramyxovirus infection

M. Iampietro, C. Dumont, C. Mathieu, J. Spanier, J. Robert, A. Charpenay, S. Dupichaud, K. P. Dhondt, N. Aurine, R. Pelissier, M. Ferren, S. Mely, D. Gerlier, U. Kalinke, B. Horvat

This study shows that paramyxoviruses like NiV and MeV activate the cGAS/STING pathway, leading to type-I interferon production and host protection against infection.

bioRxiv · Dec 26, 2020Immunology