Author

V. Fung

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4 Bioengineering· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 6 Research Focus:cell signaling & trafficking· 4 Research Focus:cell type annotation· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:development & morphogenesis· 2 Organism:E. coli· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

M. K. Levings· 4 shared M. Mojibian· 4 shared B. T. Fife· 2 shared J. Gillies· 2 shared K. Zhou· 2 shared M. Haque· 2 shared M. Speck· 2 shared P. C. Orban· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 28 mutual co-author links

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4 shared papersImmunology

M. K. Levings

Mutual co-authors in cluster

Author profile →

6 papers

Recent·Most cited

CAR Tregs mediate linked suppression and infectious tolerance in islet transplantation

C. Wardell, V. Fung, E. Chen, M. Haque, J. Gillies, J. Spanier, M. Mojibian, B. T. Fife, M. K. Levings

A2-CAR Tregs reduce BDC2.5 T cell engraftment, proliferation, and cytokine production, protecting mice from diabetes and inducing systemic tolerance.

bioRxiv · Apr 6, 2024 · PreprintImmunology

Insulin B peptide-MHC class II-specific chimeric antigen 1 receptor-Tregs prevent autoimmune diabetes

J. A. Spanier, V. Fung, C. M. Wardell, M. H. Alkhatib, Y. Chen, L. A. Swanson, A. J. Dwyer, M. E. Weno, N. Silva, J. S. Mitchell, P. C. Orban, M. Mojibian, C. B. Verchere, B. T. Fife, M. K. Levings

This paper demonstrates that InsB-g7 CAR Tregs specific for an insulin B-chain peptide prevent autoimmune diabetes in NOD mice.

bioRxiv · Feb 23, 2023 · PreprintImmunology

Engineering Escherichia coli to produce aromatic chemicals from ethylene glycol

S. Panda, J. F. J. Zhou, M. Feigis, E. Harrison, X. Ma, V. Fung, R. Mahadevan, K. Zhou

This study engineers Escherichia coli to produce aromatic chemicals from ethylene glycol, achieving higher yields than glucose and demonstrating feasibility with waste PET-derived EG.

bioRxiv · Jan 8, 2023 · PreprintBioengineering

Integration of exogenous and endogenous co-stimulatory signals by CAR-Tregs

I. Rosado-Sanchez, M. Haque, K. Salim, M. Speck, V. Fung, D. Boardman, M. Mojibian, G. Raimondi, M. K. Levings

This study compares CAR-Treg function with different co-stimulatory domains, finding in vivo equivalence between CARs with and without CD28 despite in vitro differences.

bioRxiv · Nov 10, 2022 · PreprintImmunology

Improving glycine utilization in Escherichia coli

V. Fung, D. Z. J. Tan, K. Zhou

This study engineers Escherichia coli to utilize glycine as a carbon and nitrogen source, identifying a stable pathway and genetic modifications that enhance its metabolic efficiency.

bioRxiv · Oct 10, 2022 · PreprintBioengineering

Functional effects of chimeric antigen receptor co-receptor signaling domains in human Tregs

N. A. Dawson, I. Rosado Sanchez, G. Novakovsky, V. Fung, Q. Huang, E. McIver, G. Sun, J. Gillies, M. Speck, P. C. Orban, M. Mojibian, M. K. Levings

This study compares ten CAR signaling domains in Tregs, finding that wild-type CD28 CARs are most effective in suppressing graft-versus-host disease.

bioRxiv · Aug 29, 2019Immunology