ImmunologybioRxiv
12-Lipoxygenase Governs the Innate Immune Pathogenesis of Islet Inflammation and Autoimmune Diabetes
A. Kulkarni, A. R. Pineros, S. Ibrahim…·R. M. Anderson
This study shows that 12-LOX promotes islet inflammation and autoimmune diabetes by enhancing macrophage infiltration and migration via CXCR3.