Author

M. Hoek

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1 Pathology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:cell type annotation· 3 Assay:proteomics· 3 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:clustering· 1 Organism:mouse· 1 Assay:multiome· 1

Frequent Co-Authors

A. Bondt· 2 shared A. J. R. Heck· 2 shared A. Barendregt· 1 shared A. Dwivedi· 1 shared A. Giannakopulos· 1 shared A. Hakimi· 1 shared A. Kholomeev· 1 shared A. Kreutzmann· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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2 shared papersImmunology

A. Bondt

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Parallelized Acquisition of Orbitrap and Astral Analyzers Enables High-Throughput Quantitative Analysis.

H. Stewart, D. Grinfeld, A. Giannakopulos, J. Petzoldt, T. Shanley, M. Garland, E. Denisov, A. Peterson, E. Damoc, M. Zeller, T. Arrey, A. Pashkova, S. Renuse, A. Hakimi, A. Kuehn, , C. Hock

The paper introduces a new hybrid mass spectrometer combining Orbitrap and Astral analyzers to enable faster and more sensitive high-resolution accurate mass MS/MS spectra acquisition for proteomics.

bioRxiv · Jun 2, 2023Cell Biology

Humans have distinct repertoires of IgA1

K. Dingess, M. Hoek, D. van Rijswijck, S. Tamara, M. A. den Boer, M. Damen, A. Barendregt, M. Romijn, H. G. Juncker, B. J. van Keulen, G. Vidarsson, J. van Goudoever, A. Bondt, A. J. R. Heck

This study identifies two distinct structural populations of IgA1 in human serum and milk, with different clonal repertoires and origins.

bioRxiv · Apr 8, 2022Immunology

IgG1 responses following SARS-CoV-2 infection are polyclonal and highly personalized, whereby each donor and each clone displays a distinct pattern of cross-reactivity against SARS-CoV-2 variants

D. M. H. van Rijswijck, A. Bondt, M. Hoek, K. van der Straten, T. G. Caniels, M. Poniman, D. Eggink, C. B. E. M. Reusken, G. J. de Bree, R. W. Sanders, M. van Gils, A. J. R. Heck

The paper analyzes IgG1 clonal responses to SARS-CoV-2 variants in infected donors, finding unique and polyclonal antibody repertoires with varying cross-reactivity across variants.

bioRxiv · Feb 24, 2022Immunology

APOL1 is not expressed in proximal tubules and is not filtered

N. A. Blessing, Z. Wu, S. Madhavan, M. K. Shin, M. Hoek, J. R. Sedor, J. F. O'Toole, L. A. Bruggeman

The study examines APOL1 expression in the kidney using transgenic mice and finds it is not expressed in proximal tubules or filtered by them.

PLOS ONE · Jun 17, 2021Peer-reviewedPathology