Author

A. Hakimi

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Biochemistry· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Organism:mouse· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1

Frequent Co-Authors

B. Nixon· 2 shared E. Damoc· 2 shared F. Kuo· 2 shared J. Hsieh· 2 shared K. Capistrano· 2 shared M. Do· 2 shared M. Li· 2 shared M. Liu· 2 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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2 shared papersImmunology

B. Nixon

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Protein Coronas on Functionalized Nanoparticles Enable Quantitative and Precise Large-Scale Deep Plasma Proteomics

T. Huang, J. Wang, A. Stukalov, M. K. R. Donovan, S. Ferdosi, L. Williamson, S. Just, G. Castro, L. S. Cantrell, E. Elgierari, R. W. Benz, Y. Huang, K. Motamedchaboki, A. Hakimi, T. Arrey, , D. Hornburg

This paper demonstrates that nanoparticle-based proteomics workflows enable accurate and scalable deep plasma proteomics with high precision and statistical power for biomarker discovery.

bioRxiv · Aug 28, 2023 · PreprintBiochemistry

Parallelized Acquisition of Orbitrap and Astral Analyzers Enables High-Throughput Quantitative Analysis.

H. Stewart, D. Grinfeld, A. Giannakopulos, J. Petzoldt, T. Shanley, M. Garland, E. Denisov, A. Peterson, E. Damoc, M. Zeller, T. Arrey, A. Pashkova, S. Renuse, A. Hakimi, A. Kuehn, , C. Hock

The paper introduces a new hybrid mass spectrometer combining Orbitrap and Astral analyzers to enable faster and more sensitive high-resolution accurate mass MS/MS spectra acquisition for proteomics.

bioRxiv · Jun 2, 2023Cell Biology

IRF8 Governs Tumor-Associated Macrophage Control of T Cell Exhaustion

B. Nixon, F. Kuo, M. Liu, K. Capistrano, M. Do, R. Franklin, X. Wu, E. Kansler, R. Srivastava, T. Purohit, A. Sanchez, L. Vuong, C. Krishna, H. Morse, J. Hsieh, , M. Li

This study identifies IRF8 as a key factor in tumor-associated macrophages (TAMs) that induce T cell exhaustion by presenting cancer antigens, and shows its association with poor patient survival in renal cell carcinoma.

bioRxiv · Mar 12, 2020 · PreprintImmunology

TGFβ Suppresses Type 2 Immunity to Cancer

M. Liu, F. Kuo, K. Capistrano, D. Kang, B. Nixon, W. Shi, C. Chou, M. Do, S. Li, E. Stamatiades, Y. Chen, J. Hsieh, A. Hakimi, I. Taniuchi, T. Chan, M. Li

This study shows that blocking TGFβ signaling in CD4+ T cells enhances type 2 immunity, promoting tumor healing and halting cancer progression through IL-4-mediated vasculature repair.

bioRxiv · Mar 4, 2020 · PreprintImmunology