Author

A. Pashkova

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:benchmarking· 2 Approach:experimental assay· 2 Assay:proteomics· 2 Approach:deep learning· 1 Research Focus:differential expression· 1 Organism:human· 1 Assay:metabolomics· 1 Research Focus:software / tool· 1

Frequent Co-Authors

A. Makarov· 2 shared A. Peterson· 2 shared C. Hock· 2 shared D. Hermanson· 2 shared E. Damoc· 2 shared E. Denisov· 2 shared H. Stewart· 2 shared J. Petzoldt· 2 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersBiochemistry

A. Makarov

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Paradigm shift in biomarker translation: a pipeline to generate clinical grade biomarker candidates from DIA-MS discovery

Q. Fu, M. Vegesna, N. Sundararaman, E. Damoc, T. N. Arrey, A. Pashkova, E. Mengesha, P. Debbas, S. Joung, D. Li, S. Cheng, J. Braun, D. P. B. McGovern, C. Murray, Y. Xuan, J. E. Van Eyk

This paper introduces TEAQ, a software tool that selects clinical-grade biomarker candidates from DIA-MS data by evaluating protein quantification metrics in a discovery cohort.

bioRxiv · Mar 20, 2024 · PreprintBiochemistry

Evaluating the performance of the Astral mass analyzer for quantitative proteomics using data independent acquisition

L. R. Heil, N. E. Damoc, T. N. Arrey, A. Pashkova, E. Denisov, J. Petzoldt, A. Peterson, C. Hsu, B. C. Searle, N. Shulman, M. Riffle, B. Connolly, B. X. MacLean, P. M. Remes, M. Senko, , M. J. MacCoss

The paper evaluates the Astral mass analyzer's performance in quantitative proteomics, showing it quantifies 5 times more peptides per unit time than existing Orbitrap mass spectrometers and detects over 5,000 plasma proteins.

bioRxiv · Jun 3, 2023 · PreprintBiochemistry

Parallelized Acquisition of Orbitrap and Astral Analyzers Enables High-Throughput Quantitative Analysis.

H. Stewart, D. Grinfeld, A. Giannakopulos, J. Petzoldt, T. Shanley, M. Garland, E. Denisov, A. Peterson, E. Damoc, M. Zeller, T. Arrey, A. Pashkova, S. Renuse, A. Hakimi, A. Kuehn, , C. Hock

The paper introduces a new hybrid mass spectrometer combining Orbitrap and Astral analyzers to enable faster and more sensitive high-resolution accurate mass MS/MS spectra acquisition for proteomics.

bioRxiv · Jun 2, 2023Cell Biology