Author

M. Holdorf

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Organism:virus· 1

Frequent Co-Authors

A. Hyrina· 2 shared A. Frank· 1 shared A. Lindeman· 1 shared A. Proudfoot· 1 shared C. Jones· 1 shared C. Russ· 1 shared D. Bussiere· 1 shared D. Chen· 1 shared

Activity by Year

2019-2019 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersMicrobiology

A. Hyrina

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2 papers

Recent·Most cited

MicrobiologybioRxivJul 30, 2019

A genome-wide CRISPR screen identifies ZCCHC14 as a host factor required for hepatitis B surface antigen production

A. Hyrina, C. Jones, D. Chen…·M. Holdorf

The paper uses a genome-wide CRISPR screen to identify ZCCHC14 as a host factor required for hepatitis B surface antigen production and shows it stabilizes HBsAg through RNA tailing with TENT4A/B.

DOI 10.1016/j.celrep.2019.10.113

humanexperimental assay

𝕏 PostBluesky

BiophysicsbioRxivFeb 2, 2019

First Crystal Structure of a Non-Structural Hepatitis E Viral Protein Identifies a Putative Novel Zinc-Binding Protein

A. Proudfoot, A. Hyrina, M. Holdorf…·D. Bussiere

The paper determines the crystal structure of a non-structural HEV protein, revealing a zinc-binding motif and structural homology to a fatty acid binding domain.

DOI 10.1128/jvi.00170-19

virusprotein structure

𝕏 PostBluesky