BiophysicsbioRxiv
Lipid flipping in the omega-3 fatty-acid transporter
T. Gonen, D. Matthies, C. Nguyen…·M. J. Gallenito
This study reports cryo-EM structures of Mfsd2a, revealing the Na+-dependent lipid flipping mechanism for omega-3 fatty acid transport across the BBB and identifying disease-associated mutants.