M. J. McDonald

This study shows that bacteriophages adapt to the mammalian gut mucosa through mutations and recombination, gaining a fitness advantage by altering their binding to mucin glycans.

This study tracks phenotypic and molecular evolution in 205 yeast populations over 10,000 generations, revealing patterns of declining adaptability, mutation accumulation, and genetic parallelism.

This paper reports the adaptive evolution of a genomically recoded E. coli strain to improve its fitness and identifies mutations that enhance its growth in defined media.