Author

M. J. RodrIguez-Colman

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Cancer Biology· 1

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:organoid / primary culture· 1 Approach:wet-lab / biochemical assay· 1

Frequent Co-Authors

B. M. Burgering· 1 shared E. C. A. Stigter· 1 shared H. C. Clevers· 1 shared J. Drost· 1 shared M. C. Gulersonmez· 1 shared M. C. Ludikhuize· 1 shared M. Meerlo· 1 shared N. T. B. Nguyen· 1 shared

Activity by Year

2021-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

B. M. Burgering

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1 paper

Recent·Most cited

Cancer BiologybioRxivNov 11, 2021

Rewiring glucose metabolism improves 5-FU efficacy in glycolytic p53-deficient colorectal tumors

M. C. Ludikhuize, S. Gevers, N. T. B. Nguyen…·M. J. RodrIguez-Colman

This study shows that rewiring glucose metabolism enhances 5-FU efficacy in p53-deficient colorectal tumors by altering nucleotide pools without increasing toxicity in healthy cells.

DOI 10.1038/s42003-022-04055-8

humanorganoid / primary culture

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