BiophysicsProceedings of the National Academy of SciencesPeer-reviewed
Visualization of the HIV-1 Env Glycan Shield Across Scales
Z. T. Berndsen, S. Chakraborty, X. Wang…·A. B. Ward
This study uses cryo-EM, computational modeling, and mass-spectrometry to analyze the HIV-1 Env glycan shield's structure and dynamics, revealing how heterogeneity and interactions affect epitope accessibility and trimer stability.