Cancer BiologybioRxivPreprint
Mutant EGFR is a preferred SMURF2 substrate of ubiquitination: role in enhanced receptor stability and TKI sensitivity
P. Ray, K. Raghunathan, A. Ahsan…·D. Ray
This paper identifies SMURF2-mediated ubiquitination of EGFR mutants as a mechanism enhancing receptor stability and TKI sensitivity.
DOI 10.1101/2020.04.02.022012