Author

K. Raghunathan

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:proteomics· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:imaging· 1 Assay:metagenomics· 1

Frequent Co-Authors

A. K. Kenworthy· 2 shared A. Ahsan· 1 shared A. M. Kabbani· 1 shared A. T. Shah· 1 shared C. V. Kelly· 1 shared D. Ray· 1 shared E. Kolobova· 1 shared H. Oller· 1 shared

Activity by Year

2019-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 10 mutual co-author links

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2 shared papersBiophysics

A. K. Kenworthy

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Therapy Development for Microvillus Inclusion Disease using Patient-derived Enteroids

M. Kalashyan, K. Raghunathan, H. Oller, M.-T. Bayer, L. Jimenez, J. T. Roland, E. Kolobova, S. J. Hagen, J. D. Goldsmith, M. D. Shub, J. R. Goldenring, I. Kaji, J. R. Thiagarajah

This study uses patient-derived enteroids to model Microvillus Inclusion Disease and identifies therapeutic strategies targeting Notch signaling and chloride channels.

bioRxiv · Jan 28, 2023 · PreprintCell Biology

Mutant EGFR is a preferred SMURF2 substrate of ubiquitination: role in enhanced receptor stability and TKI sensitivity

P. Ray, K. Raghunathan, A. Ahsan, U. S. Allam, S. Shukla, V. Basrur, S. Veatch, T. S. Lawrence, M. K. Nyati, D. Ray

This paper identifies SMURF2-mediated ubiquitination of EGFR mutants as a mechanism enhancing receptor stability and TKI sensitivity.

bioRxiv · Apr 2, 2020 · PreprintCancer Biology

Structured clustering of the glycosphingolipid GM1 is required for membrane curvature induced by cholera toxin

A. M. Kabbani, K. Raghunathan, W. I. Lencer, A. K. Kenworthy, C. V. Kelly

This study shows that cholera toxin subunit B induces membrane curvature only when bound to multiple GM1 receptors, highlighting the importance of structured clustering for this process.

bioRxiv · Jan 22, 2020Biophysics

Graphene nanoflakes for acute manipulation of membrane cholesterol and transmembrane signaling

K. E. Kitko, T. Hong, R. M. Lazarenko, R. J. Montenegro-Burke, A. T. Shah, Y. Zhang, K. Raghunathan, A. K. Kenworthy, M. C. Skala, J. A. McLean, Y.-Q. Xu, Q. Zhang

This study shows graphene nanoflakes manipulate membrane cholesterol, altering cell signaling in fibroblasts and neurons.

bioRxiv · Mar 18, 2019 · PreprintCell Biology