A molecular switch between mammalian MLL complexes dictates response to Menin-MLL inhibition
Y. M. Soto-Feliciano, F. J. Sanchez-Rivera, F. Perner…·C. D. Allis
The paper identifies a molecular switch between MLL1-Menin and MLL3/4-UTX complexes that determines response to Menin-MLL inhibitors in leukemia.