Author

S. Hormoz

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 2 Biophysics· 1 Cancer Biology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Approach:statistical model· 2 Organism:bacteria (other)· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. Z. Rosenthal· 2 shared J. Escabi· 2 shared S. Liu· 2 shared A. Mullally· 1 shared B. Kamaz· 1 shared C. R. Reilly· 1 shared D. J. DeAngelo· 1 shared D. Sritharan· 1 shared

Activity by Year

2017-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 31 mutual co-author links

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2 shared papersMicrobiology

A. Z. Rosenthal

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Fitness of a clonal population can be inferred from lineage trees without knowledge of the biological details

J. Escabi, S. Hormoz

This paper shows that fitness and mutation timing can be inferred from lineage trees without needing detailed biological parameters.

bioRxiv · Sep 9, 2022 · PreprintEvolutionary Biology

Collective polymerase dynamics emerge from DNA supercoiling during transcription

S. Sevier, S. Hormoz

The paper models how DNA supercoiling affects RNA polymerase motion and predicts collective polymerase behavior during transcription.

bioRxiv · Nov 24, 2021Biophysics

Droplet-based single cell RNA sequencing of bacteria identifies known and previously unseen cellular states

R. A. McNulty, D. Sritharan, S. Liu, S. Hormoz, A. Z. Rosenthal

The paper uses droplet-based single cell RNA sequencing to analyze bacterial populations, identifying known and previously unseen cellular states.

bioRxiv · Mar 10, 2021 · PreprintMicrobiology

Reconstructing the lineage histories and differentiation trajectories of individual cancer cells in JAK2-mutant myeloproliferative neoplasms

D. Van Egeren, J. Escabi, M. Nguyen, S. Liu, C. R. Reilly, S. Patel, B. Kamaz, M. Kalyva, D. J. DeAngelo, I. Galinsky, M. Wadleigh, E. S. Winer, M. R. Luskin, R. M. Stone, J. S. Garcia, , S. Hormoz

This study reconstructs the lineage histories and differentiation trajectories of JAK2-mutant HSCs in MPN patients, finding the mutation occurs decades before diagnosis and drives exponential growth of mutated HSC populations.

bioRxiv · Aug 24, 2020Cancer Biology

Metabolic Interactions Between Dynamic Bacterial Subpopulations

A. Z. Rosenthal, Y. Qi, S. Hormoz, J. Park, S. H.-J. Li, M. Elowitz

This study shows clonal bacterial populations can exhibit metabolic specialization through dynamic state-switching to manage overflow metabolites like acetate.

bioRxiv · Oct 25, 2017Microbiology