Cell BiologybioRxiv
R51Q SNX10 induces osteopetrosis by promoting uncontrolled fusion of monocytes to form giant, non-functional osteoclasts
M. Barnea, M. Stein, S. Winograd-Katz…·A. Elson
This study identifies R51Q SNX10 mutation as a cause of osteopetrosis by promoting abnormal monocyte fusion into non-functional giant osteoclasts.
DOI 10.1242/jcs.254979