Cancer BiologybioRxiv
Momelotinib is a highly potent inhibitor of FLT3-mutant AML
M. Azhar, Z. Kincaid, M. Kesarwani…·M. Azam
This study shows momelotinib is a potent FLT3 inhibitor effective against FLT3-mutant AML, including resistant variants, and suppresses resistance mechanisms like FLT3 ligand and cytokine signaling.