FOXO dictates initiation of B cell development and myeloid restriction in common lymphoid progenitors
L. Pena-Perez, S. Kharazi, N. Frengen…·R. Mansson
The paper shows that FOXO1 and FOXO3 are essential for B cell development and myeloid restriction in common lymphoid progenitors, with their combined loss causing developmental block and loss of B cell lineage.