Author

M. Kosmac

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Approach:experimental assay· 1 Organism:non-human primate· 1 Assay:proteomics· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

A. K. Thotakura· 1 shared A. Kovaltsuk· 1 shared C. M. Deane· 1 shared D. F. Kelly· 1 shared D. Melvin· 1 shared E. Oelmann· 1 shared E. Pring· 1 shared E. Richardson· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

A. K. Thotakura

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Characterisation of the immune repertoire of a humanised transgenic mouse through immunophenotyping and high-throughput sequencing

E. Richardson, S. Binter, M. Kosmac, M. Ghraichy, V. von Niederhäusern, A. Kovaltsuk, J. D. Galson, J. Trück, D. F. Kelly, C. M. Deane, P. Kellam, S. Watson

The paper characterizes the immune repertoire of a humanised transgenic mouse using immunophenotyping and high-throughput sequencing, showing similarities to human BCR repertoires.

bioRxiv · Jun 27, 2022Immunology

A novel antibody targeting ICOS increases intratumoural cytotoxic to regulatory T cell ratio and induces tumour regression.

R. C. A. Sainson, A. K. Thotakura, M. Kosmac, G. Borhis, N. Parveen, R. Kimber, J. Carvalho, S. Henderson, K. Pryke, T. Okell, S. O'Leary, S. Ball, L. Gamand, E. Taggart, E. Pring, , M. McCourt

This paper develops an antibody targeting ICOS that improves the TEFF:TReg ratio and induces tumour regression in preclinical models.

bioRxiv · Sep 16, 2019 · PreprintCancer Biology