J. Trück

The paper characterizes the immune repertoire of a humanised transgenic mouse using immunophenotyping and high-throughput sequencing, showing similarities to human BCR repertoires.

The paper compares IgH repertoire metrics across different B cell subpopulations and finds distinct patterns associated with their developmental stages and constant region positions.

The paper structurally characterizes B-cell receptor paratopes in humans and mice, showing structural differences across B-cell differentiation stages and conservation in naive repertoires.