Alveolar epithelial type 1 cells serve as a cell of origin for lung adenocarcinoma with distinct molecular and phenotypic presentation
M. Yang, H. Shen, P. Flodby, M. Koss, R. Bassiouni, Y. Liu, T. Jashashvilli, T. R. Stueve, D. J. Mullen, A. L. Ryan, J. Carpten, A. Castaldi, W. D. Wallace, B. Zhou, MD, Z. Borok, C. N. Marconett
This study identifies alveolar epithelial type 1 cells as a potential cell of origin for lung adenocarcinoma, showing distinct molecular and histological features based on cell of origin.
bioRxiv · Oct 29, 2022 · PreprintCancer Biology