C. N. Marconett

The paper identifies GRAMD2+ alveolar type I cells as plastic and capable of transitioning through multiple lung epithelial cell states in organoid culture.

This study identifies LINC00261 as a gene that reduces mutation accumulation, confers cisplatin resistance, and alters the tumor-immune microenvironment in lung adenocarcinoma.

This study identifies alveolar epithelial type 1 cells as a potential cell of origin for lung adenocarcinoma, showing distinct molecular and histological features based on cell of origin.

The paper develops novel immortalized human alveolar epithelial cell lines that can form organoids and exhibit lineage memory, offering a new in vitro model for distal lung biology and disease.