Author

M. Kratochvil

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Organism:E. coli· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:metabolomics· 1 Organism:mouse· 1 Assay:proteomics· 1 Approach:statistical model· 1 Research Focus:variant effect prediction· 1

Frequent Co-Authors

A. Long· 1 shared A. Pugliese· 1 shared C. A. F. Kuate· 1 shared C. Trefois· 1 shared G. Kaber· 1 shared H. Kuipers· 1 shared J. Yang· 1 shared K. Yadava· 1 shared

Activity by Year

2020-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperImmunology

A. Long

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2 papers

Recent·Most cited

Interrogating the effect of enzyme kinetics on metabolism using differentiable constraint-based models

S. E. Wilken, M. Besancon, M. Kratochvil, C. A. F. Kuate, C. Trefois, W. Gu, O. Ebenhoeh

This paper differentiates optimal solutions of constraint-based metabolic models to calculate sensitivities of reaction fluxes and enzyme concentrations to turnover numbers, improving parameter estimation and connecting to metabolic control analysis.

bioRxiv · Jul 11, 2022Bioengineering

Sustained Release of IL-2 Using an Injectable Hydrogel Prevents Autoimmune Diabetes

N. Nagy, G. Kaber, M. Kratochvil, H. Kuipers, S. Ruppert, K. Yadava, J. Yang, S. Heilshorn, A. Long, A. Pugliese, P. Bollyky

This paper develops an IL-2 hydrogel that prevents diabetes in NOD mice by sustained release and immune modulation.

bioRxiv · Mar 15, 2020 · PreprintImmunology