Author

M. Kuka

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 4 Assay:bulk RNA-seq· 3 Research Focus:cell type annotation· 3 Research Focus:differential expression· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Assay:CITE-seq· 1

Frequent Co-Authors

E. Sala· 4 shared M. Iannacone· 4 shared C. Laura· 2 shared M. Mangione· 2 shared V. Fumagalli· 2 shared A. Fiore· 1 shared A. O. Bigogno· 1 shared A. Schebesta· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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4 shared papersImmunology

E. Sala

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

LSD1 inhibition improves efficacy of adoptive T cell therapy by enhancing CD8+ T cell responsiveness.

I. Pallavicini, T. M. Frasconi, E. Ceccaci, S. Tiberti, C. B. Nava Lauson, E. Preto, A. O. Bigogno, M. Mangione, E. Sala, M. Iannacone, M. Kuka, L. Nezi, S. Minucci, T. Manzo

This study shows that inhibiting LSD1 enhances CD8+ T cell function in adoptive T cell therapy, leading to improved antitumor immunity and synergistic effects with anti-PDL1 therapy.

bioRxiv · Oct 27, 2023Immunology

A fluorescent reporter model for the visualization and characterization of TDC

A. Fiore, E. Sala, C. Laura, M. Riba, M. Nelli, V. Fumagalli, F. Oberrauch, M. Mangione, C. Cristofani, P. Provero, M. Iannacone, M. Kuka

This paper introduces a fluorescent reporter model to visualize and characterize TDC, showing their distinct gene signature and increased numbers during viral infection.

bioRxiv · Apr 6, 2023Immunology

The guanine nucleotide exchange factor Rin-like acts as a gatekeeper for T follicular helper cell differentiation via regulating CD28 signaling

L. Sandner, M. Alteneder, R. Rica, B. Woller, E. Sala, T. Frey, A. Tosevska, C. Zhu, M. Madern, P. Hoffmann, A. Schebesta, I. Taniuchi, M. Bonelli, K. Schmetterer, M. Iannacone, , N. Boucheron

This study identifies Rin-like as a negative regulator of Tfh differentiation in mice and humans, showing its role in CD28 signaling and endocytosis.

bioRxiv · Jun 23, 2022Immunology

Controlled administration of aerosolized SARS-CoV-2 to K18-hACE2 transgenic mice uncouples respiratory infection and anosmia from fatal neuroinvasion

V. Fumagalli, M. Rava, D. Marotta, P. Di Lucia, C. Laura, E. Sala, M. Grillo, E. Bono, L. Giustini, C. Perucchini, M. Mainetti, A. Sessa, J. Garcia-Manteiga, L. Donnici, L. Manganaro, , M. Iannacone

This study develops an aerosolized SARS-CoV-2 infection model in K18-hACE2 mice that replicates respiratory symptoms without fatal neuroinvasion, offering a more accurate representation of human COVID-19 pathogenesis.

bioRxiv · Aug 6, 2021Immunology