Protective and aggressive bacterial subsets and metabolites modify hepatobiliary inflammation and fibrosis in PSC.
M. Awoniyi, J. Wang, B. Ngo, V. Meadows, J. Tam, A. Viswanathan, Y. Lai, S. Montgomery, M. Farmer, M. Kummen, L. B. Thingholm, C. Schramm, C. Bang, A. Franke, B. Schnabl, , R. B. Sartor
This study identifies protective and aggressive bacterial subsets and metabolites in PSC patients and mice, showing their impact on hepatobiliary inflammation and fibrosis.
bioRxiv · Oct 31, 2021 · PreprintMicrobiology