Specificity and effector functions of non-neutralizing gB-specific monoclonal antibodies isolated from healthy individuals with human cytomegalovirus infection
M. L. Goodwin, H. S. Webster, H.-Y. Wang, J. A. Jenks, C. S. Nelson, J. Tu, J. Mangold, S. Valencia, J. S. McLellan, D. Wrapp, T.-M. Fu, N. Zhang, D. Freed, D. Wang, Z. An, S. R. Permar
This study characterizes non-neutralizing gB-specific monoclonal antibodies from HCMV-infected individuals, revealing their binding specificity, genotype preference, and effector functions like ADCP and ADCC.
bioRxiv · Jan 14, 2020Immunology