Author

D. Freed

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Genomics· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Research Focus:host-pathogen & immune response· 2 Research Focus:benchmarking· 1 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1 Organism:mouse· 1

Frequent Co-Authors

D. Wang· 2 shared M. Citron· 2 shared A. A. Abdulkadir· 1 shared A. Carroll· 1 shared A. English· 1 shared A. Espeseth· 1 shared A. Kolesnikov· 1 shared A. L. Reens· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersMicrobiology

D. Wang

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

The Genome In A Bottle HG002 assembly-based variant benchmark set enables comprehensive benchmarking of small and structural variants.

N. D. Olson, N. Dwarshuis, N. F. Hansen, S. Koren, A. Rhie, J. H. McDaniel, J. Wagner, G. Berry, K. Shafin, A. English, C. T. Saunders, R. Kundu, J. M. Holt, D. Freed, A. A. Abdulkadir, , Lan

The paper introduces a comprehensive variant benchmark set derived from a high-quality diploid assembly, improving small and structural variant detection across complex genomic regions.

bioRxiv · Oct 1, 2026 · PreprintGenomics

A novel rotavirus reverse genetics platform supports flexible insertion of exogenous genes and enables rapid development of a high-throughput neutralization assay

J. Wei, S. Radcliffe, M. Lu, Y. Li, J. Cassaday, W. Newhard, G. J. Heidecker, W. Rose, X. He, D. Freed, M. Citron, A. Espeseth, D. Wang

This paper develops a rotavirus reverse genetics platform enabling exogenous gene insertion and a high-throughput neutralization assay to study immune responses.

Viruses · Sep 30, 2023Peer-reviewedMicrobiology

Vaccine Hyporesponse Induced By Individual Antibiotic Treatment In Mice And Non-Human Primates Is Diminished Upon Recovery Of The Gut Microbiome

G. Swaminathan, M. Citron, J. Xiao, J. E. Norton, A. L. Reens, B. D. Topcuoglu, J. M. Maritz, K.-J. Lee, D. Freed, T. M. Weber, C. H. White, M. Kadam, E. Spofford, E. Bryant-Hall, G. Salituro, , G. D. Hannigan

This study shows that antibiotic-induced gut microbiome disruption reduces vaccine response in mice and non-human primates, but recovery of microbiome diversity restores immune responses.

bioRxiv · Apr 2, 2021Immunology

Specificity and effector functions of non-neutralizing gB-specific monoclonal antibodies isolated from healthy individuals with human cytomegalovirus infection

M. L. Goodwin, H. S. Webster, H.-Y. Wang, J. A. Jenks, C. S. Nelson, J. Tu, J. Mangold, S. Valencia, J. S. McLellan, D. Wrapp, T.-M. Fu, N. Zhang, D. Freed, D. Wang, Z. An, S. R. Permar

This study characterizes non-neutralizing gB-specific monoclonal antibodies from HCMV-infected individuals, revealing their binding specificity, genotype preference, and effector functions like ADCP and ADCC.

bioRxiv · Jan 14, 2020Immunology