PhysiologybioRxiv
LKB1 acts as a critical brake for the glucagon-mediated fasting response
S. Acevedo-Acevedo, M. L. Stefkovich, S. W. S. Kang…·N. Porat-Shliom
This study shows LKB1 suppresses the glucagon-induced fasting response in the liver, leading to metabolic inefficiency and prolonged fasting despite increased food intake.
DOI 10.1002/hep4.1942